OCT Reveals Scattering Changes After MWA in Esophagus

Sevde Etoz worked with Ryan Niemeier and other collaborators from Biomedical Engineering to study whether optical coherence tomography (OCT) could be used to characterize the effects of microwave ablation in esophagus. In particular, the study identified changes in optical scattering in the visible and near-infrared spectra that correspond to histological evidence of cell death. We hypothesize that the scattering changes are due to changes in protein conformation and cell structure due to thermal injury. The results of this study will help support future studies that could lead to an integrated therapy/feedback system for ablating and verifying treatment in the esophagus.

Read the full text: https://doi.org/10.1364/BOE.9.001648

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